Valine and non-essential amino acids affect bi-directional transport rates of leucine and isoleucine in bovine mammary epithelial cells
“Valine and non-essential amino acids affect bi-directional transport rates of leucine and isoleucine in bovine mammary epithelial cells”. This study assessed transport rates of 7 AA to evaluate the effects of high and low concentrations of Val and Ala, Gln, and Gly provided as a group in primary bovine mammary epithelial cells. Treatment effects on Leu and Ile were attributed to increased intracellular concentrations of non-essential AA used as exchange currency combined with the reduced shared transporter competition from Val. These results demonstrate that the efficiency of branched-chain amino acid uptake by mammary cells is affected by competition among the branched-chain AA and the synergistic effects of non-essential AA.
Virginia Agricultural Experiment Station
Hatch Program of the National Institute of Food and Agriculture, U.S. Department of Agriculture
National Animal Nutrition Program
National Institute of Food and AgricultureFind out more...