Virginia Tech
Browse
1/2
32 files

Real-time fMRI neurofeedback on smokers

Data acquired during real-time fMRI experiment on smokers

In previous real-time functional magnetic resonance imaging neurofeedback (rtfMRI-NF) studies on smoking craving, the focus has been on within-region activity or between-region connectivity, neglecting the potential predictive utility of broader network activity. Moreover, there is debate over the use and relative predictive power of individual-specific and group-level classifiers. This study aims to further advance rtfMRI-NF for substance use disorders by using whole-brain rtfMRI-NF to assess smoking craving-related brain patterns, evaluate the performance of group-level or individual-level classification (n = 31), and evaluate the performance of an optimized classifier across repeated neurofeedback runs. Using real-time individual-level classifiers derived from whole-brain support vector machines, we found that classification accuracy between crave and no-crave conditions and between repeated neurofeedback runs increased across repeated runs at both individual and group levels. Within the classification, individual-level accuracy was significantly greater than group-level accuracy, highlighting the potential increased utility of an individually-trained whole-brain classifier for volitional control over brain patterns to regulate smoking craving. This study provides evidence supporting the feasibility of using whole-brain rtfMRI-NF to modulate smoking craving-related brain responses and the potential for learning individual strategies through optimization across repeated feedback runs.

Funding

NIH DA026086

History

Publisher

University Libraries, Virginia Tech

Corresponding Author Name

Pearl Chiu

Corresponding Author E-mail Address

chiup@vtc.vt.edu

Files/Folders in Dataset and Description

[Files] - NIfTI format in each zip file with naming convention subXXX.zip XXX refers to anonymized index of subject used in the analysis. Within each zip file run1/2/3 refers to the order of the fMRI runs during our task paradigm. crv or ncrv means ‘craving’ or ‘don’t crave’ conditions adopted in the experimental paradigm.

Usage metrics

    Virginia Polytechnic Institute and State University

    Exports

    RefWorks
    BibTeX
    Ref. manager
    Endnote
    DataCite
    NLM
    DC